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mRNA vaccines in the spotlight

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Proposals to ban mRNA vaccines aren’t just rooted in misinformation – they risk further politicizing science and blocking research and access to future lifesaving medical breakthroughs. mRNA technology is already being explored to treat cancers, rare diseases, and many infectious diseases including HIV, influenza, and rabies (5,81,82). 

We’ve tackled some of the most persistent myths in this post – each one is unpacked in a short, shareable slide. But this isn’t our first time covering these claims. Many have already been explored in greater detail (some more than once!). You can find a list of deeper dives in the sources linked.

5 common myths about COVID-19 vaccines | ScienceUpFirst | October 2024

How COVID-19 vaccines were made so quickly | ScienceUpFirst & Vox | February 2021

COVID-19 mRNA vaccines are not going to change your DNA | ScienceUpFirst | Sept. 2021

Misinformation about COVID-19 vaccines and cardiac events | ScienceUpFirst | March 2024

There are NOT more people dying because of the COVID-19 vaccine. | ScienceUpFirst | Mars 2023

“Turbo cancer” is not real. COVID-19 vaccines don’t cause cancer. | ScienceUpFirst | April 2024

How does the COVID vaccine affect menstruation? | ScienceUpFirst | August 2022

Let’s talk COVID-19 and fertility | ScienceUpFirst | July 2021

Get the facts about Fertility and COVID-19. | ScienceUpFirst | April 2022

What is “Immunity Debt” and is it a real thing? | ScienceUpFirst | November 2022

Vaccines make the immune system stronger | ScienceUpFirst | September 2021

Can the COVID-19 vaccines cause autoimmune disorders? | ScienceUpFirst | Dec. 2023

Let’s talk about spike proteins | ScienceUpFirst | June 2021

Misinformation continues to spread about Spike Proteins | ScienceUpFirst | December 2021

You asked, we answered: April 2024 | ScienceUpFirst | May 2024

Sources
  1. The long road to mRNA vaccines | CIHR | October 2021
  2. mRNA vaccines, explained | Vox
  3. Understanding COVID-19 mRNA Vaccines | August 2021
  4. mRNA vaccines for infectious diseases: principles, delivery and clinical translation | Nature Reviews Drug Discovery | August 2021
  5. MRNA Vaccines, Once a Trump Boast, Now Face Attacks From Some in GOP | KFF Health News | March 2025
  6. COVID-19 mRNA vaccines | Government of Canada | September 2022
  7. Vaccine development and approval in Canada | Government of Canada | April 2021
  8. How Did We Get COVID-19 Vaccines So Fast? | Vaccine Bulletin | February 2021
  9. COVID-19 vaccine safety: Report on side effects following immunization | Government of Canada | January 2024
  10. Canadian Adverse Events Following Immunization Surveillance System (CAEFISS) | Government of Canada | February 2025
  11. Surveillance | Canadian Paediatric Society | June 2024
  12. The facts about COVID-19 vaccines | Government of Canada | May 2022
  13. Statement from the Council of Chief Medical Officers of Health (CCMOH): Update on COVID-19 Vaccines and the Risk of Myocarditis and Pericarditis | Government of Canada | October 2021
  14. Myocarditis and Pericarditis After mRNA COVID-19 Vaccination: 2024 Status and Management Update | Canadian Journal of Cardiology | September 2024
  15. Vaccine Safety Systems | CDC 
  16. COVID-19 Vaccine Safety Surveillance | FDA | January 2025
  17. Safety of COVID-19 vaccines | European Medicines Agency (EMA)
  18. Causality assessment of an adverse event following immunization (‎AEFI)‎: user manual for the revised WHO classification, 2nd ed., 2019 update | WHO | April 2021
  19. Coronavirus Disease 2019 (COVID-19) Vaccine Safety | CDC | January 2025  
  20. Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar | Nature Communications | January 2023
  21. COVID-19 vaccine doses administered | Government of Canada | June 2024
  22. Thrombosis with thrombocytopenia syndrome: Findings from the Advisory Committee on Causality Assessment | Government of Canada | May 2024
  23. From DNA to RNA – Molecular Biology of the Cell | NCBI Bookshelf
  24. Myths & Facts About COVID-19 Vaccines | CDC | August 2024
  25. What are mRNA vaccines and how do they work? | MedlinePlus Genetics
  26. Messenger RNA-based vaccines: Past, present, and future directions in the context of the COVID-19 pandemic | Advanced Drug Delivery Reviews | October 2021
  27. The dawn of mRNA vaccines: The COVID-19 case | Journal of Controlled Release | March 2021
  28. Swedish study on COVID vaccines and DNA misinterpreted | AP News | July 2022
  29. No, COVID mRNA Vaccines Won’t Damage Your DNA | Scientific American | January 2024
  30. Fact Check: mRNA vaccines do not turn humans into ‘hybrids’ or alter recipients’ DNA | Reuters | April 2021
  31. COVID-19 Vaccine Basics | CDC | September 2024
  32. COVID-19 Vaccines Have Not Been Shown to Alter DNA, Cause Cancer | FactCheck.org | October 2023
  33. False claims persist about COVID-19 vaccine-linked “turbo cancers” | Public Health Communications Collaborative | August 2023
  34. COVID-19 Vaccines Have Not Been Shown to Cause ‘Turbo Cancer’ | FactCheck.org | August 2023
  35. Fact Check: No evidence COVID-19 vaccines cause ‘turbo cancer’ | Reuters | December 2022
  36. Good Question: Why Are Some Cancers More Aggressive Than Others? | CBS Minnesota | July 2017
  37. Plasmid-gate: Debunking the DNA contamination claims in mRNA vaccines | Global Vaccine Data Network | October 2024
  38. COVID-19 Vaccines and People with Cancer | National Cancer Institute | October 2023
  39. There is no evidence linking COVID-19 vaccines with diseases like cancer or HIV | Health Desk | October 2021
  40. COVID-19 Vaccines in People with Cancer | American Cancer Society | September 2024
  41. Fact Check: No evidence COVID-19 vaccines have caused increase in cancers, contrary to claims made on social media | Reuters | February 2022
  42. Fact Check: No evidence COVID-19 vaccines cause cancer | Reuters | November 2021
  43. Response to Dr. Ladapo’s letter | U.S. Food & Drug Administration | December 2023
  44. Residual DNA in COVID-19 mRNA vaccines is documented, isn’t associated with genome modification or cancer, contrary to claim by Robert Malone | Science Feedback | November 2023
  45. Autoimmune response found in many with COVID-19 | National Institutes of Health (NIH) | September 2021
  46. Full article: Emergence of Post COVID-19 Vaccine Autoimmune Diseases: A Single Center Study | Infection and Drug Resistance | February 2023
  47. New‐onset autoimmune phenomena post‐COVID‐19 vaccination | Immunology on Wiley Online Library | December 2021
  48. SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity | Nature Communications on PubMed Central | March 2023
  49. Long-term risk of autoimmune diseases after mRNA-based SARS-CoV2 vaccination in a Korean, nationwide, population-based cohort study | Nature Communications | July 2024
  50. Insights into new-onset autoimmune diseases after COVID-19 vaccination | Autoimmunity Reviews on PubMed Central | April 2023 
  51. Risk of autoimmune diseases following COVID-19 and the potential protective effect from vaccination: a population-based cohort study | eClinicalMedicine | September 2023
  52. COVID‐19 vaccine triggers autoimmune disease? Possible mechanism and current evidence | International Journal of Rheumatic Diseases | November 2023
  53. Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility | American Journal of Epidemiology | January 2022
  54. The impact of COVID-19 vaccines on fertility-A systematic review and meta-analysis | Vaccine on ScienceDirect | October 2022
  55. Does mRNA SARS-CoV-2 vaccine influence patients’ performance during IVF-ET cycle? | Reproductive Biology and Endocrinology | May 2021
  56. Does the SARS-CoV-2 mRNA vaccine and its serum IgG levels affect fertility treatments and obstetric outcomes? An observational cohort study | Clinical and Experimental Medicine | April 2024
  57. In Vitro Fertilization and Early Pregnancy Outcomes After Coronavirus Disease 2019 (COVID-19) Vaccination | Obstetrics & Gynecology | April 2022
  58. Ovarian follicular function is not altered by SARS–CoV-2 infection or BNT162b2 mRNA COVID-19 vaccination | Human Reproduction | September 2021
  59. Exposure of Ovaries to COVID-19 Vaccination DOes Not Impair Fertility | Fertility and Sterility | September 2021
  60. COVID-19 infection and vaccine have no impact on in-vitro fertilization (IVF) outcome | Scientific Reports | December 2022
  61. COVID-19 Vaccination Does Not Affect Reproductive Health Parameters in Men | Frontiers in Public Health | February 2022
  62. Sperm Parameters Before and After COVID-19 mRNA Vaccination | JAMA | June 2021
  63. COVID-19 Vaccine Questions and Answers for Healthcare Professionals | CANVax
  64. Investigating trends in those who experience menstrual bleeding changes after SARS-CoV-2 vaccination | Science Advances | July 2022
  65. Association between SARS-CoV-2 vaccination and healthcare contacts for menstrual disturbance and bleeding in women before and after menopause: nationwide, register based cohort study | The BMJ | May 2023
  66. Association Between Menstrual Cycle Length and Coronavirus Disease 2019 (COVID-19) Vaccination | Obstetrics & Gynecology | April 2022
  67. Covid-19 vaccination and menstrual cycle length in the Apple Women’s Health Study | npj Digital Medicine | November 2022
  68. Effect of COVID-19 vaccination on the timing and flow of menstrual periods in two cohorts | Frontiers in Reproductive Health | July 2022
  69. COVID-19 vaccination and menstrual cycle characteristics: A prospective cohort study | Vaccine on PubMed Central | June 2023
  70. Explainer on COVID19 vaccine and fertility | Summary of current studies made by Viki Male, Senior Lecturer in Reproductive Immunology at Imperial College London | Last update July 2024
  71. A prospective cohort study of preconception COVID-19 vaccination and miscarriage | Human Reproduction | December 2023
  72. Immune System and Vaccines | Children’s Hospital of Philadelphia
  73. Questions & Answers| Immunize Canada
  74. Explaining How Vaccines Work | CDC | August 2024
  75. Spike Protein Behavior| Science | May 2021
  76. Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients| Clinical Infectious Diseases | February 2022
  77. Spike Protein Circulating in the Vaccinated: What does it mean? | Deplatform Disease | May 2021
  78. SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness | Nature | August 2020 
  79. mRNA vaccine spike protein differs from viral version | Scope by Stanford Medicine | July 2023
  80. SARS-CoV-2 and the spike protein in endotheliopathy | Trends in Microbiology on ScienceDirect | January 2024
  81. Trump administration at ‘war’ with mRNA technology: scientists alarmed vaccine skeptics could kill research | The Guardian | March 2025
  82. States push fight against mRNA vaccines | AXIOS | March 2025

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